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Page 1
Targeting IRAK4 for Degradation with PROTACs.
ACS Med Chem Lett. 2019 Jun 14;10(7):1081-1085. doi: 10.1021/acsmedchemlett.9b00219. eCollection 2019 Jul 11.
ACS Med Chem Lett. 2019.
PMID: 31312412
Free PMC article.
Selective CDK6 degradation mediated by cereblon, VHL, and novel IAP-recruiting PROTACs.
Anderson NA, Cryan J, Ahmed A, Dai H, McGonagle GA, Rozier C, Benowitz AB.
Anderson NA, et al. Among authors: mcgonagle ga.
Bioorg Med Chem Lett. 2020 May 1;30(9):127106. doi: 10.1016/j.bmcl.2020.127106. Epub 2020 Mar 10.
Bioorg Med Chem Lett. 2020.
PMID: 32184044
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Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode.
Down K, Amour A, Anderson NA, Barton N, Campos S, Cannons EP, Clissold C, Convery MA, Coward JJ, Doyle K, Duempelfeld B, Edwards CD, Goldsmith MD, Krause J, Mallett DN, McGonagle GA, Patel VK, Rowedder J, Rowland P, Sharpe A, Sriskantharajah S, Thomas DA, Thomson DW, Uddin S, Hamblin JN, Hessel EM.
Down K, et al. Among authors: mcgonagle ga.
J Med Chem. 2021 Sep 23;64(18):13780-13792. doi: 10.1021/acs.jmedchem.1c01102. Epub 2021 Sep 11.
J Med Chem. 2021.
PMID: 34510892
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Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids.
Calder ED, McGonagle FI, Harkiss AH, McGonagle GA, Sutherland A.
Calder ED, et al. Among authors: mcgonagle ga.
J Org Chem. 2014 Aug 15;79(16):7633-48. doi: 10.1021/jo5014492. Epub 2014 Aug 1.
J Org Chem. 2014.
PMID: 25060853
Free article.
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